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pentobarbital will lessen the extent or outcome of lefamulin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Steer clear of coadministration of lefamulin with strong or average CYP3A inducers Except if the advantage outweighs dangers. Watch for minimized efficacy.pentobarbital will lower the extent or influe

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